Intellectual Thoughts by Sanjay Panda


Dishman buys Solvay fine chemicals

Dishman Pharmaceuticals & Chemicals has made another incursion into European assets by signing a memorandum of understanding to acquire the fine chemicals, vitamin D and vitamin D analogues business of Solvay Pharmaceuticals at Veeenendaal, Netherlands। The deal is expected to close within four months। Dishman added that the acquisition”will not only increase the basket of products of Dishman but also bring in new customer relationships”.

Indications are that vitamin D3 production will be transferred to India, thus bringing more fine chemicals expertise there, while the other products will remain in the Netherlands. For Solvay, the sale of the two businesses will enable it to focus more on its core areas of cardio-metabolic and neuroscience treatments.

More importantly, Dishman’s existing contract under to supply about 90 tonnes/year of the API for Teveten (Eprosartan Mesylate), Solvay’s anti-hypertensive drug, will not change. The contract expires in December 2008, but can be renewed annually until its patent protection ends in 2013. Since an FDA inspection at its Bavla site in 2006, Dishman has been able to supply this API for use in the US as well as Europe.Separately, Dishman has announced the integration of another of its previous European acquisitions, SynProTec DCR of the UK, into CarboGen-Amcis.

SynProTec DCR specialises in process research and custom synthesis of pharmaceutical intermediates and has capacity of up to 4,500 litres for production of early phase APIs and large-scale intermediates. Griffiths said that capacity combined capacity will increase and material produced at SynProTec DCR can be further processed at CarboGen Amcis’s Swiss facilities.

Safety & driving: Driving in flood waters


  • If you live in an area where flooding may occur, move your vehicle to higher ground if flooding is expected. As well as the risk of damage to your vehicle by leaving it in a flooded area, it may also be a hazard or cause obstruction to emergency services.
  • Do not drive unless your journey is absolutely necessary.
  • If you have to drive in a flooded area take care. Do not attempt to drive through water if you are unsure of the depth.
  • Don't drive through fast-moving water, such as at a flooded bridge approach – your car could be swept away
  • Drive slowly and steadily to avoid creating a bow wave, and allow on-coming traffic to pass first.
  • Keep the engine revving by slipping the clutch otherwise water in the exhaust could stall the engine.
  • Modern vehicles are fitted with catalytic converters in the exhaust system. The catalyst normally works at high temperatures and may crack if it is submerged in water. Replacement catalysts are expensive.
  • The air intake on many modern cars is located low down at the front of the engine bay and it only takes a small quantity of water sucked into the engine to cause serious damage. All engines are affected but turbo-charged and diesel engines are most vulnerable.
  • Be considerate – driving through water at speeds above a slow crawl can result in water being thrown onto pavements, soaking pedestrians or cyclists.
  • If your car stalls, immediately abandon it and climb to higher ground. Watch your footing. Just six inches of fast-moving flood water can sweep a person off his or her feet.
  • Test your brakes as soon as you can after driving through water.
  • If the vehicle has been stood in the flooded area for any prolonged period contact your local dealer for further advice.
  • If the vehicle has only been in a flood for a short period, drive with extreme caution and take the car to be checked at the earliest opportunity.