Bayer and Monsanto to Create a Global Leader in Agriculture

In the largest deal of 2016 (so far), after months of negotiations  with several  baby steps  agriculture giants Bayer and Monsanto announced  that  they are planning to merge. In an  all-cash   transaction    Bayer  striking the deal a $128  a share  valuing Monsanto at $66B.  including the debt.

Consolidation has been driven by a global  glut that has pushed down crop prices and hurt farm incomes, leading to reduced investment in agricultural inputs such as fertilisers and  Agrochemicals.   Several Mega & small mergers are right now underway/partially completed   like Dow Chemical and DuPont, ChemChina &   Syngenta, FMC & Cheminova  etc.

But the proposed merger  likely face an intense and lengthy regulatory process If the deal closes, it will create a company commanding more than a quarter of the combined world market for seeds and pesticides in the fast-consolidating farm supplies industry.

Both the   company executives claims the  businesses are complimentary & there is very little overlap between them.  However antitrust experts have said regulators  likely  demand the sale of some soybeans, cotton and canola seed assets.

The transaction includes a $2-billion break-up fee that Bayer will pay to Monsanto should it fail to get regulatory clearance. Bayer expects the deal to close by the end of 2017.

Can NSG be far behind? as India enters MTCR.

India became the 35th member of the Missile Technology  Control Regime (MTCR) as the members of the international anti-proliferation grouping agreed to admit India in the regime. The decks were cleared for India’s entry when it joined the Hague Code of Conduct against Ballistic Missile Proliferation.

MTCR is the first step for India’s entry in the four export control bodies, including the NSG (essentially  founded in response to the  Indian nuclear test in May 1974) , the Wassenaar  Arrangement and the Australia Group.   Entry & membership   of  few of  these  groups would end decades of denial of  some technology  &  further   will enable India to become a major supplier/player in the global missile market,   the technology  available in house now.  Over the years, it has developed technology that allows it to make missiles that precisely hit the targets.

While the NSG is focused on stemming the proliferation of nuclear weapons, the Wassenaar Arrangement establishes lists of items for which member countries are to apply export controls. Australia Group formed in 1985 prompted by Iraq’s use of chemical weapons during the Iran-Iraq War.

Only a few days ahead of  the MTCR clincher, India’s bid to enter the much-coveted  Nuclear Suppliers Group (NSG) was denied by  China, a  member in the group,  by blocking it.  China, has been  playing  the spoilsport  since long  but an entry to MTCR  should  not be long  before India takes its due  & deserve  seat in the NSG  which Is been pending since long.

CRISIL rings Warning Bell for Indian Pharma Companies

A new Crisil report  made it clear how fast the Indian pharma sector needs to shift away from export-oriented manufacture of generics and the just process improvement  exercise, towards investing in R&D to develop new molecules and biosimilars  

Sellers of copycat drugs in developed markets may see exports fall by 10-12% in the next five years as fewer drugs go off-patent in these markets,  compare to  CAGR  of 19% seen in the last decade. CRISIL Research said. The deceleration likely to be much more post 2020.

Between 2011 and 2015, Indian companies accounted for an average of 37% of all abbreviated new drug application (ANDA) approvals—which enable a company to sell generic versions of innovator molecules —in the US market. This was about  similar   to 40%  share held by US companies, but way ahead of the next competing countries—Israel and Germany—which had 5% each.

Non availability of any   further off patent  block buster  and  fall  in growth rate  of   US generic market, the writing on the wall for Indian drug-makers is clear: They have to move up the value-chain, from making cheap copies of off-patent drugs to creating and owning intellectual property through new discovery and biosimilars. To be sure, they have increased R&D spending significantly over the years. Top 30 companies research spending was 6.5% of revenues in FY15, compared to 3.8%  a decade back. However, this pales in comparison with global majors, who spend close to 16%.

Moreover, the Crisil report points out, much of the Indian companies’ expenditure is  for launching generic therapies, changing product mix in generics, and process development. Besides, the atmosphere of doubt over drug quality—in the wake of the FDA’s crackdown—further dampens Indian generic-makers’ export-prospects. 

CRISIL Research analysis indicates that 14  Indian companies together have 39 products in various stages of clinical development. These companies have adopted various approaches—such as in-house development, joint development and out-licensing—to manage the risk-return trade-off.  However, no one has launched a new molecule in a regulated market such as the US.

Thus far,  it is  disappointing in NCE effort  but  39 product in the pipeline should be an encouraging sign for Indian pharma’s prospects. The key challenge will be to uphold drug-quality and pass the approval hurdles in well-regulated jurisdictions like the US.

Tesla Model 3- "Biggest one-week launch of any product ever."

Tesla announced on 8^th April that it has received 325,000 pre orders for its recently unveiled Model 3. If it sells every car that's been reserved, the company says it will earn enough revenue to make this the "biggest one-week launch of any product ever."   

Approx $14 billion in implied future sales for a car that  unlikely  to  delivered  to anybody  until 2018 at the earliest.  While it’s undoubtedly encouraging that hundreds of thousands of consumers are eager to purchase the Model 3, its possible that interest may wane if some deliveries are pushed back until 2020  and that  seems likely if one sees the  history of Tesla.

Musk further  revealed that only 5 percent of Model 3 pre order customers reserved two cars -'the maximum allowed"  and  as per him,   this suggests "low levels of speculation," or buyers looking to flip the car for a profit. The reservations are not transferable, meaning any speculators would need to buy the car outright and then sell it used to a third-party.

After receiving these incredible numbers of pre orders  Tesla now seems to be scaling back on Model 3 expectation. For instance, when Musk first introduced the Model 3, he insinuated that Supercharging would be free. However, a closer inspection of Musk’s remarks revealed that Supercharging capabilities on the Model 3 would come standard, perhaps implying that Model 3 users might have to pay for Supercharging access.

In fact, Tesla even changed the supercharging verbiage on its website following the Model 3’s unveiling. Whereas “Supecharging” was initially listed as one of the Model 3’s features, it has since been changed to “Supercharging Capable.”

Other   instances like, Tesla’s initial Model 3 webpage boasted that the car would sport a “5-star Safety Rating in all categories.” but the updated Model 3 webpage simply states that the car will be “Designed for Safety.”

In another example, the first incarnation of the Model 3 webpage said that the car will feature “Autopilot Safety Features.” Now it simply reads that the Model 3 will come with “Autopilot Hardware”, seemingly implying that users will have to pay extra to get Autopilot safety features turned on.

Source :website and various news articles

10 facts about China's Five-Year Plan for 2016 to 2020

1. To grow China's economy  by an average of at least 6.5% a year over the period. Gross domestic product (GDP) to go from 67.7 trillion yuan ($10.4 trillion) last year to more than 92.7 trillion yuan in 2020.


2. The service sector to account for 56% of GDP by 2020, up from 50.5% in 2015.


3. To cap total energy consumption under 5 billion tons equivalent of coal by 2020, compared with 4.3 billion tons equivalent of coal last year.
 
4. To cut energy consumption and carbon dioxide emissions per unit of GDP by 15% and 18% respectively from 2015 levels by 2020.


5. City air quality to be rated "good" or better at least 80% of the time by 2020, up from 76.7% in 2015.


6. To raise installed nuclear power capacity to 58 gigawatts by 2020, when another 30 gigawatts are scheduled to be under construction. Currently, 28.3 gigawatts are installed, with 26.7 under construction.


7. To expand the high-speed railway network to 30,000 kilometres  by 2020, from 19,000 kilometres last year, and build at least 50 new civilian airports.


8. To boost per capita disposable income by 6.5% or higher every year. The figure grew by 7.4% in 2015.


9. To create a total of 50 million jobs in urban areas over the five years.


10. Permanent urban residents to make up 60% of China's total population by 2020, up from 56.1% last year.