Intellectual Thoughts !!!!!: 2020


Saturday, May 2, 2020

FDA allows emergency use of drug remdesivir for COVID 19


The US Food and Drug Administration on Friday authorized Remdesivir (a nucleoside ribonucleic acid (RNA) polymerase inhibitor) an experimental antiviral drug, for emergency use to treat Covid-19.


The authorization allows the intravenous drug to be distributed to doctors to administer to patients with severe disease.

Many health experts have had high hopes for the drug, which was initially developed by Gilead Sciences to treat Ebola. In past,it was also  used in experiments to treat the coronaviruses SARS and MERS. That early testing gave remdesivir a head start in the race for a treatment to Covid-19.


The NIH trial, called the Adaptive COVID-19 Treatment Trial, included 1,063 patients. The results showed that the median time to recover for patients who randomly received the placebo was 15 days while patients who received remdesivir had a median recovery time of 11 days. Remdesivir also lowered the mortality rate compared to the placebo group, from 11.6 percent to 8 percent.

These results, however, are preliminary. There are at least 19 studies on remdesivir around the world underway or in planning stages, some recruiting thousands of patients. It will be several months before they yield definitive answers, but they will, hopefully, bring the world closer to a working treatment.

Earlier  a randomized trial of the drug in China recently published in the Lancet  found that there was no statistical benefit to taking the drug. The study  was based on a true randomized controlled trial from Wuhan, China, with 237 patients. The study was also peer-reviewed by other scientists. Initially, the authors wanted to include up to 450 patients, but the lockdown imposed in the city meant that patients stopped arriving.

The FDA on 28th March, 2020  had approved  emergency use authorization to a malaria drug, hydroxychloroquine, after President Donald Trump repeatedly promoted it as a possible treatment for COVID-19. 

Here is the link to the announcement.



Sunday, March 15, 2020

India's Namaste Greeting Go Global Amid Coronavirus Outbreak


India prides itself on popularizing yoga and meditation in many parts of the world. Its looks like another practice   the traditional greeting, the "namaste", described as “virus-proof,” goes global as some world leaders adopt it amid the coronavirus pandemic.


Hand hygiene has emerged as the foremost preventive measure against the spread of coronavirus and this has sidelined the handshake, the 'namaste' is increasingly becoming popular.


"Namaste,” a combination of two Sanskrit words Namas & Te, translates into “bowing to you” and does not involve skin contact and allows people to maintain a distance.  

Here is embed video   from BBC


Sunday, February 23, 2020

Mumbai Police sets up Punishing Signal to stop unnecessary honking. (watch the video)



There is a truth universally acknowledged by drivers in India: Honk your horn loud enough and the traffic lights will surely change to green. 

How many times has it happened that you are standing at a traffic signal and people waiting behind you kept honking repeatedly, even when the light was red? 


Fed up of impatient drivers, police in Mumbai have come up with a new system to punish those who cannot wait at traffic lights in silence.


The new system, said the police, was quite simple: “Honk more, wait more.”

Known as “the punishing signal”, Mumbai police installed a rigged traffic light system to tackle the problem of “reckless honkers”, which resets  the red traffic signal to a longer duration,  every time the sound of horns goes above 85 decibels and  one need  to wait more.

Great Idea!!!!! This will surely  bring discipline  and responsibility among the drivers in Mumbai.


Please  see the video  which was released by Mumbai Police.